Alnylam Pharmaceuticals, Inc. is an American biopharmaceutical company focused on the discovery, development and commercialization of RNA interference (RNAi) therapeutics for genetically defined diseases. The company was founded in 2002 and is headquartered in Cambridge, Massachusetts. In 2016, Forbes included the company on its "100 Most Innovative Growth Companies" list.
| trading_symbol | registrant_name | time | price | change | percentage_change |
|---|---|---|---|---|---|
| ALNY | ALNYLAM PHARMACEUTICALS, INC. | 2026-10-15 14:21:48 | 231.84 | 7.34 | 3.27 |
| trading_symbol | central_index_key | registrant_name | isin_number | lei_number | ein_number | exchange | sic_code | sic_description | fiscal_year_end | state_of_incorporation | address_street | address_city | address_state | address_zip_code | address_country | address_country_code | phone_number | mailing_address | business_address | former_name | industry | founding_date | chief_executive_officer | number_of_employees | website | market_cap | shares_issued | shares_outstanding | description | update_time |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ALNY | 0001178670 | ALNYLAM PHARMACEUTICALS, INC. | US02043Q1076 | 529900S3ZI14OWRJII50 | 770602661 | Nasdaq | 2834 | Pharmaceutical Preparations | 1231 | — | 675 WEST KENDALL STREET | CAMBRIDGE | MA | 02142 | UNITED STATES | US | (617) 551-8200 | 675 WEST KENDALL STREET, CAMBRIDGE, MA, 02142 | 675 WEST KENDALL STREET, CAMBRIDGE, MA, 02142 | ALNYLAM PHARMACEUTICALS INC | Pharmaceutical | 2002 | Yvonne Greenstreet | 2,500 | http://alnylam.com | 42,630,000,000 | 133,734,000 | 133,809,118 | Alnylam Pharmaceuticals, Inc. is an American biopharmaceutical company focused on the discovery, development and commercialization of RNA interference (RNAi) therapeutics for genetically defined diseases. The company was founded in 2002 and is headquartered in Cambridge, Massachusetts. In 2016, Forbes included the company on its "100 Most Innovative Growth Companies" list. | 2026-10-09 00:58:33 |
| Fiscal Year | Market Cap | Change In Market Cap | Percentage Change In Market Cap | Shares Outstanding | Change In Shares Outstanding | Percentage Change In Shares Outstanding |
|---|---|---|---|---|---|---|
| 2025 | 42,630,000,000 | 11,640,000,000 | 37.5605 | 132,623,144 | 3,165,988 | 2.4456 |
| 2024 | 30,990,000,000 | 7,340,000,000 | 31.0359 | 129,457,156 | 3,511,363 | 2.788 |
| 2023 | 23,650,000,000 | 6,053,955,780 | 34.4052 | 125,945,793 | 1,814,805 | 1.462 |
| Executive Name | Executive Position | Fiscal Year | Salary | Bonus | Stock Awards | Incentive Plan Compensation | Other Compensation | Total Compensation |
|---|---|---|---|---|---|---|---|---|
| Bryan A. Supran | Secretary, Executive Vice President, Chief Legal Officer | 2025 | 190,400 | 350,000 | 6,000,430 | 214,820 | 90,700 | 6,846,350 |
| Pushkal Garg, M.D. | Executive Vice President | 2025 | 767,900 | 0 | 3,687,650 | 1,072,500 | 22,400 | 6,490,500 |
| Yvonne L. Greenstreet, M.D. | Chief Executive Officer | 2025 | 1,404,200 | 0 | 5,512,500 | 3,562,500 | 25,020 | 14,867,600 |
| Jeffrey V. Poulton | Executive Vice President, Chief Financial Officer | 2025 | 724,400 | 0 | 3,988,480 | 950,300 | 22,400 | 6,863,800 |
| Tolga Tanguler | Chief Commercial Officer, Executive Vice President | 2025 | 698,000 | 0 | 3,687,650 | 783,200 | 20,120 | 6,129,020 |
| Fiscal Year | Employee Count |
|---|---|
| 2025 | 2,500 |
| 2024 | 2,230 |
| 2023 | 2,100 |
| Fiscal Year | 2025 | 2024 | 2023 |
|---|---|---|---|
| Revenue | 3,713,937,000 | 2,248,243,000 | 1,828,292,000 |
| Cost Of Revenue | 677,166,000 | 306,513,000 | 268,216,000 |
| Gross Profit | 3,036,771,000 | 1,941,730,000 | 1,560,076,000 |
| Research And Development Expenses | 1,319,775,000 | 1,126,232,000 | 1,004,415,000 |
| General And Administrative Expenses | 1,210,713,000 | 975,526,000 | 795,646,000 |
| Operating Expenses | 3,212,359,000 | 2,425,128,000 | 2,110,467,000 |
| Operating Income | 501,578,000 | -176,885,000 | -282,175,000 |
| Net Income | 313,747,000 | -278,157,000 | -440,242,000 |
| Earnings Per Share Basic | 2.39 | -2.18 | -3.52 |
| Earnings Per Share Diluted | 2.33 | -2.18 | -3.52 |
| Weighted Average Shares Outstanding Basic | 131,004,000 | 127,651,000 | 124,906,000 |
| Weighted Average Shares Outstanding Diluted | 134,684,000 | 127,651,000 | 124,906,000 |
| Fiscal Year | 2025 | 2024 | 2023 |
|---|---|---|---|
| Cash And Cash Equivalents | 1,657,250,000 | 966,428,000 | 812,688,000 |
| Marketable Securities Current | 1,251,234,000 | 1,719,920,000 | 1,615,516,000 |
| Accounts Receivable | 777,567,000 | 102,743,000 | 99,576,000 |
| Inventories | 82,719,000 | 78,509,000 | 89,146,000 |
| Non Trade Receivables | — | — | — |
| Other Assets Current | 281,892,000 | 116,964,000 | 126,382,000 |
| Total Assets Current | 4,050,662,000 | 3,295,285,000 | 2,982,697,000 |
| Marketable Securities Non Current | — | — | — |
| Property Plant And Equipment | 513,147,000 | 502,784,000 | 526,057,000 |
| Other Assets Non Current | 59,461,000 | 65,310,000 | 72,003,000 |
| Total Assets Non Current | 915,669,000 | 944,698,000 | 847,183,000 |
| Total Assets | 4,966,331,000 | 4,239,983,000 | 3,829,880,000 |
| Accounts Payable | 115,721,000 | 88,415,000 | 55,519,000 |
| Deferred Revenue | 4,845,000 | 55,481,000 | 102,753,000 |
| Short Term Debt | — | — | — |
| Other Liabilities Current | 1,080,197,000 | 887,472,000 | 713,013,000 |
| Total Liabilities Current | 1,466,349,000 | 1,186,272,000 | 967,786,000 |
| Long Term Debt | 1,007,784,000 | 1,024,621,000 | 1,020,776,000 |
| Other Liabilities Non Current | 7,594,000 | 398,108,000 | 308,438,000 |
| Total Liabilities Non Current | 2,710,806,000 | 2,986,623,000 | 3,082,738,000 |
| Total Liabilities | 4,177,155,000 | 4,172,895,000 | 4,050,524,000 |
| Common Stock | 1,324,000 | 1,293,000 | 1,259,000 |
| Retained Earnings | -6,702,524,000 | -7,287,748,000 | -7,009,591,000 |
| Accumulated Other Comprehensive Income | -20,097,000 | -34,518,000 | -23,375,000 |
| Total Shareholders Equity | 789,176,000 | 67,088,000 | -220,644,000 |
| Fiscal Year | 2025 | 2024 | 2023 |
|---|---|---|---|
| Depreciation And Amortization | 55,658,000 | 56,670,000 | 54,054,000 |
| Share Based Compensation Expense | 348,235,000 | 272,084,000 | 221,680,000 |
| Other Non Cash Income Expense | — | — | — |
| Change In Accounts Receivable | 359,963,000 | 86,550,000 | 87,939,000 |
| Change In Inventories | -8,474,000 | -13,590,000 | -18,367,000 |
| Change In Non Trade Receivables | — | — | — |
| Change In Other Assets | 117,724,000 | -3,229,000 | 9,029,000 |
| Change In Accounts Payable | 75,066,000 | 91,093,000 | 80,840,000 |
| Change In Other Liabilities | — | — | — |
| Cash From Operating Activities | 524,080,000 | -8,312,000 | 104,156,000 |
| Purchases Of Marketable Securities | 1,305,081,000 | 1,634,911,000 | 1,823,501,000 |
| Sales Of Marketable Securities | 1,802,257,000 | 1,571,665,000 | 1,553,800,000 |
| Acquisition Of Property Plant And Equipment | 58,697,000 | 34,277,000 | 62,211,000 |
| Acquisition Of Business | — | — | — |
| Other Investing Activities | 2,150,000 | 117,000 | 4,438,000 |
| Cash From Investing Activities | 436,329,000 | -116,840,000 | -336,350,000 |
| Tax Withholding For Share Based Compensation | — | — | — |
| Payments Of Dividends | — | — | — |
| Issuance Of Common Stock | 229,697,000 | 284,281,000 | 114,249,000 |
| Repurchase Of Common Stock | — | — | — |
| Issuance Of Long Term Debt | — | — | — |
| Repayment Of Long Term Debt | — | — | — |
| Other Financing Activities | — | — | — |
| Cash From Financing Activities | -305,190,000 | 294,159,000 | 172,131,000 |
| Change In Cash | 690,155,000 | 153,768,000 | -53,672,000 |
| Cash At End Of Period | 1,657,250,000 | 966,428,000 | 812,688,000 |
| Income Taxes Paid | 15,088,000 | 14,360,000 | — |
| Interest Paid | 218,707,000 | 67,578,000 | 32,118,000 |
| Fiscal Year | 2025 | 2024 | 2023 |
|---|---|---|---|
| Earnings Per Share | 2.39 | -2.18 | -3.52 |
| Price To Earnings Ratio | 166.3808 | -107.9404 | -54.3778 |
| Earnings Growth Rate | -209.633 | -38.0682 | -62.1505 |
| Price Earnings To Growth Ratio | -0.7937 | 2.8354 | 0.8749 |
| Book Value Per Share | 6.0241 | 0.5256 | -1.7665 |
| Price To Book Ratio | 66.0103 | 447.7337 | -108.3567 |
| Ebitda | 637,120,000 | -65,269,000 | -264,967,000 |
| Enterprise Value | 51,444,274,600 | 30,095,749,810 | 24,116,345,460 |
| Dividend Yield | — | — | — |
| Dividend Payout Ratio | — | — | — |
| Debt To Equity Ratio | 1.277 | 15.2728 | -4.6263 |
| Capital Expenditures | 66,021,000 | 33,397,000 | 56,617,000 |
| Free Cash Flow | 458,059,000 | -41,709,000 | 47,539,000 |
| Return On Equity | 0.3976 | -4.1462 | 1.9953 |
| One Year Beta | 0.8996 | 0.5366 | 1.0324 |
| Three Year Beta | 0.8454 | 0.9546 | 0.9636 |
| Five Year Beta | 0.8993 | 0.7592 | 0.8161 |
| Insider Name | Relationship To Issuer | Transaction Date | Amount Of Securities | Acquired Or Disposed | Securities Owned Following Transaction |
|---|---|---|---|---|---|
| SUPRAN BRYAN | EVP, CLO and Secretary | 2026-10-02 | 1,758 | D | 12,807 |
| Greenstreet Yvonne | Director, Chief Executive Officer | 2026-09-19 | 107 | A | 95,802 |
| PYOTT DAVID E I | Director | 2026-06-01 | 3,830 | A | 5,412 |
| PYOTT DAVID E I | Director | 2026-06-01 | 921 | D | 4,491 |
| PYOTT DAVID E I | Director | 2026-06-01 | 1,175 | D | 3,316 |
| Name Of Reporting Person | Type Of Reporting Person | Report Date | Transaction Type | Transaction Date | Owner Type | Amount |
|---|---|---|---|---|---|---|
| Cory A Booker | Senator | 2026-09-09 | Sale (Full) | 2026-08-11 | Spouse | $1,001 - $15,000 |
| Name Of Reporting Person | Report Date | State | Transaction Type | Transaction Date | Owner Type | Amount |
|---|---|---|---|---|---|---|
| Jefferson Shreve | 2025-06-22 | IN06 | Sale | 2025-05-12 | — | $15,001 - $50,000 |
| Josh Gottheimer | 2024-02-15 | NJ05 | Sale | 2024-01-29 | Joint | $1,001 - $15,000 |
| Josh Gottheimer | 2024-02-15 | NJ05 | Purchase | 2024-01-11 | Joint | $1,001 - $15,000 |
| Josh Gottheimer | 2024-01-07 | NJ05 | Sale | 2023-12-11 | Joint | $1,001 - $15,000 |
| Daniel Goldman | 2023-04-17 | NY10 | Purchase | 2023-03-06 | — | $15,001 - $50,000 |
| Investor Name | Period Of Report | Market Value | Amount Of Securities | Price Per Security |
|---|---|---|---|---|
| Activest Wealth Management | 2026-09-30 | 247 | 1 | 247 |
| HCR Wealth Advisors | 2026-09-30 | 227,987 | 924 | 246.7392 |
| Blue Trust, Inc. | 2026-09-30 | 15,051 | 61 | 246.7377 |
| Curated Wealth Partners LLC | 2026-09-30 | 270,179 | 1,095 | 246.7388 |
| Generali Investments CEE, investicni spolecnost, a.s. | 2026-09-30 | 1,158,966 | 3,850 | 301.0301 |
| Registrant Name | Period Of Report | Fund Name | Fund Symbol | Amount Of Units | Value In Usd | Percentage Value Compared To Assets |
|---|---|---|---|---|---|---|
| TRUST FOR PROFESSIONAL MANAGERS | 2026-08-31 | Column Mid Cap Fund | CFMCX | 841 | 202,420.29 | 0.0181 |
| ETF Series Solutions | 2026-07-31 | Aptus Large Cap Upside ETF | UPSD | 2,959 | 608,133.68 | 0.5197 |
| AMERICAN CENTURY STRATEGIC ASSET ALLOCATIONS INC | 2026-07-31 | R5 CLASS | AACGX | 771 | 158,455.92 | 0.0571 |
| AMERICAN CENTURY STRATEGIC ASSET ALLOCATIONS INC | 2026-07-31 | R6 CLASS | AACDX | 771 | 158,455.92 | 0.0571 |
| AMERICAN CENTURY STRATEGIC ASSET ALLOCATIONS INC | 2026-07-31 | C CLASS | AACCX | 771 | 158,455.92 | 0.0571 |